JAX® Mouse Diversity Genotyping Array Service

Based on an innovative JAX-designed high-resolution genotyping array

Key features

  • An innovative genotyping microarray designed for high-density, genome-wide profiling of single nucleotide polymorphisms (SNPs)
  • Covers 100 times more SNPs than any other available mouse array
  • Can simultaneously assay over 620,000 phylogenetically informative SNPs
  • SNPs spaced approximately one every 4.3kb across the genome and highly polymorphic among characterized mouse strains
  • Yields highly reliable genotypes

Applications

  • Association and quantitative trait loci (QTL) studies
  • Genetic quality control
  • Characterizing or comparing mouse DNA samples (e.g. from tumor tissues, cell lines, substrains, or sister strains)
  • High resolution mapping and genetic analysis
  • Copy number variation (CNV) analysis
  • Population genetics studies

Two service levels

Basic service:

  • An array for each sample
  • DNA quality control check (high molecular weight DNA)
  • Sample preparation and array hybridizations with your DNA samples
  • Brief report consisting of methods and QC diagnostics
  • Delivery of raw data, library file, genotypes, and list of SNPs polymorphic among samples

Custom service adds:

  • Study design consultation
  • Comparisons between selected samples
  • Report consisting of methods, QC diagnostics, and summary statistics for each sample and each comparison
  • Additional customized SNP data analysis, such as comparisons with previously-reported genotypes

Pricing for basic service

  • $760/array for 10 or fewer arrays
  • $695/array for 11-29 arrays
  • $660/array for 30 or more arrays
  • Fee covers the array, reagents, processing
  • If tissue samples are submitted, the fee for genomic DNA extraction is $40/sample