Patient-derived xenograft resource
The Jackson Laboratory has partnered with more than 20 cancer clinics to provide access to a wider range of patient-derived xenograft (PDX) cancer models at earlier passage numbers than any other PDX resource available today. More than 200 PDX oncology models from treatment naive and resistant patients have been established in the highly immunodeficient NSG (005557) mouse strain. JAX® In Vivo Pharmacology Services can conduct efficacy testing in any PDX cancer model or distribute tumor-bearing mice to your laboratory.
To help you choose the most appropriate tumors for your PDX cancer study, information on patient clinical history and genomics data sets are available at no cost. Standard of care data are also available for many models. Frozen tumor tissue and prepared slides are available for biomarker analysis at a nominal cost.
Available PDX tumor types include:
Visit the Mouse Tumor Biology database to search for specific models and access data.
Contact us today for more information.