Oncology preclinical services
JAX preclinical oncology services provide highly customizable in vivo compound evaluation to help clients and researchers evaluate novel anti-cancer therapies.
We offer diverse oncology study protocols that range from traditional xenograft (subcutaneous and orthotopic) services to patient-derived xenograft (PDX) cancer models and advanced humanized (hCD34+ or hBLT) mouse models for cancer drug development. We have the flexibility to customize studies and import client-provided mice and cancer cell lines.
Off-the-shelf, patient-derived xenograft cancer models ready for enrollment by you or our study directors.
A comprehensive collection of PDX tumor models for compound efficacy testing.
Assessment of tumor growth rate and drug efficacy in a multitude of human cancer cell lines.
Evaluation of tumor cell drug response within the organ of origin via bioluminescent imaging.