JAX compound evaluation: neuromuscular and neurodegenerative disorders

JAX compound evaluation services combine proven models of Duchenne's with high-throughput test platforms.

Duchenne's muscular dystrophy (DMD)

  • Compound testing in a spontaneous model of DMD
  • Model: C57BL/10ScSn-Dmdmdx/J
  • Readouts:
    • Grip strength measurement
    • Locomotor testing
    • Rotarod
    • Forced exercise and exhaustion
    • Histopathology
  • Sample study: Mouse Model for Duchenne's Muscular Dystrophy (.pdf)

 

In vivo pharmacology services facility

JAX® In Vivo Pharmacology services are performed in our West Sacramento, California facility. We would be happy to arrange a tour.

Humanized NSG mice

The ideal platform for studying hematopoiesis, inflammatory disease and human-specific pathogens

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