JAX® In Vivo services for inflammation and autoimmunity
Experimental methods
- Dosing by all commonly used routes including:
per os (p.o., gavage) intramuscular (i.m.) intrarectal (i.r.) intravenous (i.v.) subcutaneous (s.c.) food, water intraperitoneal (i.p.) intradermal (i.d.) osmotic pump - Tissue harvest
- Biospecimen collection
Selected disease models
| Disease Area | Mouse Model |
|---|---|
| Asthma | (000651) BALB/cJ |
| Alopecia Areata | (000659) C3H/HeJ (transplantation) |
| Rheumatoid Arthritis | (000670) DBA/1J (collagen induced) |
| Systemic Lupus Erythematosus | (100008) NZBWF1/J (006825) MRL/MpJ-Faslpr/2J |
| Inflammatory Bowel Disease | (004326) C3Bir.129P2(B6)-Il10tm1Cgn/Lt DSS (in C57BL/6J) TNBS (in BALB/cJ) |
Standard protocols
- Asthma sample study (.pdf)
- Collagen-Induced Arthritis sample study (.pdf)
- Collagen Antibody-Induced Arthritis sample study (.pdf)
- Experimental Autoimmune Encephalomyelitis (EAE) sample study (.pdf)
- Evaluation of Cell Replacement Therapy for Type 1 Diabetes in Mice (.pdf)
- Allograft Rejection sample study (.pdf)
Supporting services
- Histopathology - The Jackson Laboratory and UC Davis Comparative Pathology Lab (CPL)
- Blood chemistry - The Jackson Laboratory and UC Davis CPL
- A network of supporting service proviers offering biomarker analysis and specialty imaging modalities
