In Vivo Services for cancer researchers
Under the direction of Dr. Neal Goodwin, the JAX® In Vivo Services cancer program provides highly customizable preclinical oncology services to help customers evaluate novel anticancer therapies. We offer a breadth of technologies that span from traditional xenograft services to advanced humanized mouse models of cancer.
Sample studies
- Sample orthotopic prostate tumor study (.pdf)
- Lung Cancer Xenograft protocol (.pdf)
- Teratoma Formation Assay protocol (.pdf)
Technical strengths
- Xenograft, orthotopic, and endogenous mouse model platforms for multiple human cancer therapeutic areas
- State-of-the-art phenotyping laboratory featuring high-throughput, cost-effective, and non-invasive test platforms for characterizing models, evaluating key physiological parameters, validating drug targets, and testing drug efficacy
- Non-invasive bioluminescent imaging
- Flexibility to customize studies and import client-provided animals and cancer cell lines
Why work with The Jackson Laboratory?
- Facilitated access to our best JAX® Mice cancer models including the NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (005557) mouse for developing humanized mouse models of cancer
- Ph.D. study directors and technical staff dedicated specifically for cancer in vivo services
- Highly skilled experts at dosing and testing drug efficacy in over 100 mouse models, including diverse cancer models
- Support from our extensive research staff, which includes over 200 Ph.D.s, M.D.s, and D.V.M.s
