Inventoried DIO mice

The Jackson Laboratory now offers Diet-Induced Obese (DIO) C57BL/6J male mice in inventory in limited quantities from 6 through 26 weeks of age. Age matched male C57BL/6J mice fed a control diet are also available. To help researchers stay current with the availability levels of these mice we now provide weekly DIO Mice Inventory Reports via email.

Protocol for DIO B6 inventory mice

The protocol for feeding and care of DIO C57BL/6J males is as follows: Male mice are selected at random at 4 weeks of age and fed a 6% chow diet (Lab Diet® 5k52).  At six weeks of age, mice are placed in wean cages in groups of 10 and are fed either the study diet (Research Diets, Inc. D12492i, 60 kcal% fat) or the control diet (Research Diets, Inc. D12450Bi, 10 kcal% fat). Mice have ad libitum access to food and water. Mice are weighed at 6, 12 and 18 weeks of age primarily to acclimate them to handling. The mice are not individually identified. Mice are housed in animal room MP-21. The most recent health report for this room can be found here.

Figure 1. Mean body weights (g +/- SEM) for groups of B6 males (n=20-44) fed 10% and 60% diets from 6 to 17 weeks of age. Figure 2. Mean blood glucose levels (mg/dl +/- SEM) for groups of 17- to 19-week old B6 males (n=10-33) fed 10% and 60% fat diets for 11-13 weeks (data obtained by glucose tolerance test).

JAX® Inventoried DIO Mice Fact Sheet (pdf)


Ordering information

Orders can be placed for immediate shipment for mice available in inventory or may be scheduled to be shipped at a later date with additional (or modified) feeding protocol. To place an order for these mice please send an e-mail to DIOemail@jax.org or call 1-800-422-MICE (6423) and ask for a DIO representative. These mice can also be sent to our In Vivo Services group to conduct study protocols to your specifications. Please contact your Regional Jackson Laboratory Representative or JAX® Services if you would like to learn more about our In Vivo Services capabilities.

In Vivo Efficacy Testing Services Fact Sheet (pdf)

JAX® made-to-order DIO mice

We will custom make DIO B6 mice to meet your specific research requirements either using standard protocols we have developed or custom protocols. DIO Services are available from both our Bar Harbor, Maine and Sacramento, California facilities. Click here to learn more or contact your Regional Jackson Laboratory Representative for a quotation.

DIO Services Fact Sheet (pdf)

Bibliography of relevant DIO references


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