JAX® Compound Evaluation Services
Our compound evaluation services are customizable, cost-effective, and executed according to superior JAX quality standards. Our 80-year history and documented success in mouse-based research is unmatched.
Key benefits
- Experience in evaluating experimental therapies in more than 100 mouse strains in many therapeutic areas, including the following:
- cancer
- obesity and diabetes
- autoimmune and inflammatory disorders
- atherosclerosis
- skin disorders
- neuromuscular/neurodegenerative disorders
Mouse Model for Duchenne’s Muscular Dystrophy [.pdf]
- regenerative medicine
- Broad collection of test platforms for evaluating effects of compounds on key physiological processes
- Collaboration with a network of providers offering bioanalytical (LC/MS-MS), and biomarker analysis
- Access to the world's largest collection of genetically modified mouse strains
Capabilities
- Testing numerous medicinal entities, including small molecules, antibodies, siRNAs, and ES cell-derived therapies
- Inducing disease by multiple techniques, including chemical, surgical, diet, genetic, and spontaneous
- Dosing by all commonly used routes
- Collecting blood, serum, plasma, urine, and feces for in-life evaluation
- Performing necropsies and collecting tissues for histopathology, immunohistochemistry, gene expression, blood chemistry, etc.
- Executing standard or custom-designed protocols
We are continually adding new assays. Please contact us to discuss your requirements.
