JAX® Compound Evaluation Services
Customizable, cost-effective, comprehensive, and superior quality preclinical efficacy testing services using relevant mouse models of human disease.
Therapeutic areas
- cancer
- obesity and type 2 diabetes
- type 1 diabetes
- autoimmune and inflammatory disorders
- atherosclerosis
- skin disorders
- neuromuscular/neurodegenerative disorders
Mouse Model for Duchenne’s Muscular Dystrophy (.pdf)
Chronic MPTP Model of Parkinson’s Disease (.pdf)
- regenerative medicine
Capabilities
- Testing numerous medicinal entities, including small molecules, antibodies, siRNAs, and ES cell-derived therapies
- Inducing disease by multiple techniques, including chemical, surgical, diet, genetic, and spontaneous
- Dosing by all commonly used routes
- Collecting blood, serum, plasma, urine, and feces for in-life evaluation
- Performing necropsies and collecting tissues for histopathology, immunohistochemistry, gene expression, blood chemistry, etc.
- Executing standard or custom-designed protocols
We are continually adding new assays. Please contact us to discuss your requirements.
