JAX® Rederivation Service

Is the health status of your mice confounding your research results, impairing their ability to reproduce, or shortening their lives? We offer two services to restore them to a specified and opportunistic pathogen free (SOPF) health status.


Speed rederivation (including Sperm Cryo)

Key benefits

  • Quick turnaround time: 12 to 15 weeks*
  • Minimum of eight SOPF pups provided (typically 12 or more)*
  • Includes Sperm Cryo Service and two years of storage*
  • Enables future recoveries or expansions
  • Enables strain importation without quarantine
  • A convenient way to receive mice from a collaborator 

* If males are too old, we may not have sufficient sperm to freeze and cannot guarantee a minimum number of mice.

Get started today with our speed rederivation quote form

C57BL/6 vs. 129 Background Genetic Scan Characterization Panel

Our C57BL/6 vs.129 background characterization panel distinguishes between any B6 and 129 strains. It utilizes approximately 150 evenly spaced SNP markers, covering all autosomes and the X chromosome. The genome-wide spacing averages 15Mb – equivalent to approximately 8 centimorgans. This scan is ideally suited for checking a strain new to you for genetic contamination, to check how congenic it is or to document its genetic composition as part of its cryopreservation records. Price is $159.00/sample tested (typically two samples).

Details

  • Requires only two males, 10 to 16 weeks of age, from your colony 
  • Uses IVF and wild-type oocytes from the appropriate genetic background 
  • Available for transgenic, knockout, and single gene mutant mice on most commonly used genetic inbred backgrounds
  • Shipment includes comprehensive animal health report 
  • Genotyping available for additional cost

Illustration of rederivation timeline
The typical turnaround time from importation of investigator-supplied mice to arrival of SOPF mice is 12 to 15 weeks.

Custom rederivation

Key benefits

  • Best suited for rederiving inbreds, homozygotes, or strains with multiple genetic mutations
  • Minimum of two pair of SOPF mice provided

Get started today with our custom rederivation quote form

Details

 

Jonathan CohenQuarantine versus rederivation

Jonathan Cohen of Mount Sinai School of Medicine discusses quarantine versus rederivation
Video: Watch video (01:26)

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